Atomoxetine/Methylphenidate Effects on Social Play Behavior.
نویسنده
چکیده
Researchers at Utrecht University, The Netherlands, and University "Roma Tre," Rome, Italy, studied the neural substrates of the previously identified social play-suppressant effects of methylphenidate (MPH) and atomoxetine, drugs widely used for the treatment of attention-deficit hyperactivity disorder (ADHD).
منابع مشابه
Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats.
Positive social interactions during the juvenile and adolescent phases of life, in the form of social play behavior, are important for social and cognitive development. However, the neural mechanisms of social play behavior remain incompletely understood. We have previously shown that methylphenidate and atomoxetine, drugs widely used for the treatment of attention-deficit hyperactivity disorde...
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Background: The aim of this study was to directly compare efficacy of atomoxetine and methylphenidate in treatment of children and adolescents 6- 18 years. Methods: All published, randomized, open label or double blind trials, comparing the efficacy of methylphenidate with atomoxetine in treatment of children diagnosed with ADHD, using DSM-IV criteria were included in this study; ADHD...
متن کاملAtomoxetine may improve methylphenidates' efficacy in treatment of ADHD?
Methylphenidate, a psychostimulant, is first choice treatment for Attention Deficit Hyperactivity Disorder (ADHD)(Dopfner et al. 2002). Unfortunately, it has many adverse side effects, especially depression and appetite loss, which limits its dosage. There are only a few studies investigating the effect of a combination of Methylphenidate and other psychoactive substances, especially antidepres...
متن کاملComparative short term efficacy and tolerability of methylphenidate and atomoxetine in attention deficit hyperactivity disorder.
OBJECTIVE To compare the short term efficacy and tolerability of methylphenidate and atomoxetine in children with Attention deficit hyperactivity disorder (ADHD). DESIGN Open label randomized parallel group clinical trial. SETTING Child Guidance Clinic of a tertiary care hospital of Northern India from October 2010 to June 2012. PARTICIPANTS 69 patients (age 6-14 y) with a diagnosis of AD...
متن کاملAtomoxetine could improve intra-individual variability in drug-naïve adults with attention-deficit/hyperactivity disorder comparably with methylphenidate: A head-to-head randomized clinical trial.
OBJECTIVE Intra-individual variability in reaction time (IIV-RT) is common in individuals with attention-deficit/hyperactivity disorder (ADHD). It can be improved by stimulants. However, the effects of atomoxetine on IIV-RT are inconclusive. We aimed to investigate the effects of atomoxetine on IIV-RT, and directly compared its efficacy with methylphenidate in adults with ADHD. METHODS An 8-1...
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ورودعنوان ژورنال:
- Pediatric neurology briefs
دوره 29 2 شماره
صفحات -
تاریخ انتشار 2015